yes

Email:

Enter your Email address to receive your results

no

The results of your query will be available by a html file

Window size: Adapt the parameters to the window size

11

22

Window size: 11 residues (on turn) 22 residues (two turns)

Reference value

Hydrophobicity <H>

x

Minimal <H>

Maximal <H>

Enter the minimal and maximal <H> values

Hydrophobic moment <µH>

x

Minimal <µH>

Maximal <µH>

Enter the minimal and maximal <µH> values

Reference value

Minimal number of polar residues + glycine

x

Enter the minimal number of polar residue (EDKRSTNQH)+G

Minimal number of glycine

x

0 1 2 3 4 5 6 7 8

Enter the minimal number of glycine

Number of charged residues

x

Minimal

Maximal

Enter the minimal and maximal charged residues (EDKR)

Net charge z

x

Minimal

Maximal

Enter the minimal and maximal z values

Reference value

Minimal number of some unpolar residues

x

THR

ALA

ILE

LEU

VAL

PHE

TYR

TRP

MET

0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15

Enter the minimal number of selected residue

Is proline accepted ? (at i, i+3 / n-3, n)

yes

no

Is cysteine accepted ?

yes

no

Hydrophobic face detection

yes

no

A algorithm to determine Hydrophobic face (4/5 residues ACLIVMPFWY minimum and G accepted in the center) ?

Sequences length selected > 22 residues

yes

no

Display only sequences merged and plots if sequence selected > 2 turns (22 residues)

SwissProt Database

Human

Rat

Mouse

Yeast

Personnal DataBase

The personal database must be in a FASTA format

BlackList (Hypothetical, Putative, Probable)

yes

no

Elimination of protein whose designation contains one of the terms of the blacklist

WordList (limited to two words)

yes

no

Selection of protein whose designation contains one of the terms of the wordlist

One-letter code size proportional to amino acid volume

yes

no

Rotation of the helix to align vertically the <µH> vector

yes

no